Update - from now on, I will only use mutas as Kerri on DoN … 
I played this mutation as Mengsk with Kerrigan ally and he build only spire - no hydraden or omega network, but but he (with some small help from me, but I didn’t get many earthsplitters out that quickly) managed to clear the map before the 3rd night. Only defense of the south entrance was needed (as he also killed the army attacking the north on the 2nd night).
I had always trouble with ground army, as Kerrigan is slow at killing buildings just by herself and ground units (mainly lings) keep derping around and getting killed by broodlings. WIth mutas this is a non-issue and she can easily continue clearing during the night as well, with Kerrigan tanking and mutas killing everything.