There are already a lot of threads about this, but I figured i’d include some information to see if we could find some kind of correlation. As like others, it happens a lot when moving to a new area, or coming across other players, or simply entering a dungeon. My situation happens 90% of the time right when I log into the game making it unplayable from the getgo. I usually have around 50ms, but once the issue occurs, it tends to spike to 900-1596 and then I start rubber banding/nothing is responsive.
I am playing from Southern California using Frontier FIOS as my ISP with a Eero 6 router. I’ve never had any issues like this from launch until mid-way into Season 1 where I stopped playing. I recently logged in yesterday before the season started and ran into this problem, but I shrugged it off thinking it would be a one-off thing.
I am leaning more towards some kind of network problem sending/receiving packets to the D4 server, but what do I know.
edit: I currently resolved the issue by using a latency tunnel. A VPN might work similarly. At least until blizzard figures what the problem is.
edit 2: Great news! Blizzard seems to have patched and fixed the problem altogether!