I suppose it would all depend on how skilled the person is at multi-boxing. Before I go into all of that, Botting if I recall reading things correctly is an automated thingy. Meaning that a player can start something up, the game plays on its own and the only player requirement is for the player to start the stuff up and the game plays itself.
Multi-boxing on the other hand requires the player to be present. If I’m multi-boxing I have to be there and use my mouse and keyboard. If I’m not there doing anything, the game is just going to have a bunch of toons just sitting there doing idle animations.
I’m a novice multi-boxer. And in my opinion depending on the classes a player chooses and their skill at multi-boxing will determine how more efficient they can play the game. From my personal experience::
I can deal with a single mob fine. When it comes to multiple mobs, it’s a hit or miss.
I find my leveling experience slower since there is an XP penalty.
My mule that aids me. Tends to be a liability sometimes. Sometimes I forget to make them follow me after a fight, or I am running and they draw a mob that I didn’t see.
When it comes to get X item from killed mobs. I have to gather twice as many. Which means that completing quests takes a bit longer.
I’m sure there are more efficient setups than what I am using. But this works for me.
I use my mouse on account one and use a keyboard for account two. Macros are not illegal to use. I have a single macro that gets my other account to follow and ready to assist my main (Which I have to manually refresh after every fight) and then I use normal keybinds for combat abilities.
If I was botting, I wouldn’t have any of those issues and would just have my characters run off and do their own thing on a set path.