Mouse ghosting on me?

[Yager-proudmoore]

Mouse/Clicking/Movement Issues

Since the patch has dropped, I have had issues with my mouse in-game. About 85% of the time, I can barely click NPCs, my spells, or vendors and not be able to move with my mouse. I know it isn’t a hardware issue; just wondering if anyone is experiencing this same thing.

This post sounds similar to your description but there are a ton of threads on the issue.