And I prefer to have them be as accurate to the Folklore as possible!
That means Werewolves of the Devil are just disguised Illusionists while Werewolves of God look like actual Wolves, Zombies are Enslaved Undead and low-ranked Vampires are Flesh-eating Revenants that are rotting, can shapeshift into anything they want and need to be staked, garlic-d, decapitated, dismembered, burned and scattered into a River before the Full Moon in order to be killed.
As for Horror Characters from outside Horror: We need new ideas of how to approach Jekyll and Hyde honestly. Most versions of Jekyll and Hyde that change the Gender either change the name or make Hyde so obviously an Inhuman Monster(read: Fanged Furry Muppet) it’s ridiculous!
Now if we can get a Doctor Henrietta Jekyll(teacher of a school) who using the Potion turns into an Evil Dwarf about to commit depravities in School without guilt runs afoul the Hot-headed Jocks of the School and is scared back into the lab to create a Potion that removes the Animalistic traits from herself by turning them into a separate person.
Jekyll still in the Hyde persona visits the School again now no longer Animalistic and Violent enough to draw the attention of the Jocks instead draws the ire of the Queen Bees of the School due to her habit of stealing(Alcohol and Money), torturing, manipulating and gambling and she gets scared back into the lab again to get rid of the stealing, torturing, manipulating and gambling traits from herself splitting them off as a different person.
Hyde now purged of every Sin except Vanity, Sloth, Treachery, Cowardice and Pride now appears as a Medium Height Lazy Blond Snob who likes to brag to the School which gains her the ire of the Queen Bees yet again driving her back to the lab to purge the Sloth, the Backstabbing, the Snobbish Behavior and the urge to Brag resulting in a Statuesque Beautiful Blond Girl who is an all dramatic know-it-all.
Since the new form of Hyde doesn’t create waves at first she turns back into Jekyll and informs the class as teacher that she is getting put in charge in her absence. After turning back into Hyde the Queen Bees threaten her and she flees in cowardice and promptly drinks the original potion to turn back into Henrietta Jekyll for the second time.
Henrietta Jekyll decides like Henry Jekyll to denounce Hyde, abandon the Potion and donates to Charity & tries to be as good as possible and gets all smug and self-righteous with the only difference being that she used the transformation Potion twice(despite using 3 different Potions to split off undesirable traits into separate beings) and thus is not in danger of transforming back into Hyde.
Imagine a Girl Dr. Jekyll with only Pride(without Snobbish Behavior), Vanity(without the urge to Brag) and Cowardice as Buried Vices(that only surface in Hyde form and can be sensed just from being the same room as her) as all other Vices are excised utterly!