the artifact quest is undoable because at this level we don’t have demonic gateway yet which is required to get to Mephistroth.
edit: I take that back, i had to spec into fiendish stride and fel armor, with soulstone and healthstone, to get past this section. still, i don’t think that was the intended way to do it.
Also, are there supposed to be 2 skulls floating around the lock? think that’s bugged too.