Toxic Mutation Combinations!

Co-op Missions Discussion
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I love playing Brutal+ but I’ll be damned if some of the random combos of mutations are not especially difficult or annoying to play against. This thread is all about what combos you’ve faced recently that immediately made you rage quit or were just incredibly stressful to face. Note, I’m not arguing for any of these to be removed (except Microtransactions, that one just needs to die) just venting a bit of fun frustration about the Brutal+ experience.

I’ll start with a few.

1. Fatal Attraction and Mineral Shards. Are you serious, the MINERAL SHARDS cause my workers to get pulled off mining whether I attack them or they expire? That’s annoying as hell, especially considering I’m also trying to micro my army away from the pull train that is the regular version of Fatal Attraction.

2. Life Leech and Diffusion AKA, the immortal Hybrid combination. Bonus points if you add in Moment of Silence or Double edged to this combo. Good luck taking down Hybrid.

3. Micro-transactions and Slim Pickings. Just GTFO with this combo.

4. Short sighted and Long Ranged. Oh yea you see that Siege Tank or Collosus zapping your guys? Yea you’ll have to get right in their face to deal with them. Bonus points if you add Darkness to this.

5. Darkness and Short sighted. This one isn’t neccessarily difficult, but it makes the game so frustrating to play.

6. Blizzard and Nuclear Annihilation. This one is self explanatory lol.

What are some of the worst ones, you’ve been up against?

2 Likes
What riveting gameplay
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Basically anything with Fatal Attraction, Afraid of the Dark, and or Blizzard is super annoying.

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There was a weekly mutation with this combo named Death and Taxes, with those two mutators plus Black Death on DoN.

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I saw it. I could not NOPE fast enough.

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  1. Concussive Attacks and Blizzard
    I got this combination on Dead of Night as Zagara. Between the Blizzards being certain death for my units if they blew over them and being slowed long-term even after escaping one the blizzards, it ended up being the longest Dead of Night I’ve ever played.
  2. Photon Overload and Mineral Shields
    This one was basically a diet coke version of yours with Fatal Attraction, but it meant that attacking the Mineral Shields would cause them to attack my workers. Not nearly as crippling but still annoying.
  3. Propogators and Speed Freaks
    It doesn’t matter what other mutations are attached to this combination, this combination is basically instant death. I’ve rolled this multiple times, and every time this mutation happens, one or both of our bases have been melted down into propogators within the first 10 minutes. I’d argue that almost any mutation with Propogators in general is toxic, but this combination, in my opinion, is the worst.
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  1. Propagator/Short Sighted/Speed Freak.
  2. Propagator/Short Sighted/We Move Unseen.
  3. Propagator/Short Sighted/Evasive Maneuvers.
  4. Propagator/Fatal Attraction/Speed Freak.
  5. Propagator/Long Ranged/Short Sighted.
  6. Propagator/Heroes of the Storm/Evasive Maneuvers.
    …
    Yea, I can do this for day. Anything that have Propagator in them is cancerous.
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2. Life Leech and Diffusion AKA, the immortal Hybrid combination. Bonus points if you add in Moment of Silence or Double edged to this combo. Good luck taking down Hybrid.

The only weakness this has is out ranging diffusion, so the worst 3rd mutator would be short sighted that forces you close I would think. And/Or more fatal attraction.

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Meh this sh*t sounds ez to deal with. Try double edged, hardened will, just die and hero’s of the storm combo on brutal +6. Then well talk

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I am pretty sure it doable on Void Launch with two static defensive commanders.

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I’ve never seen a win for leech + diffusion. I lost leech, diffusion, and speed on DoN recently. Can you post a video or replay for winning that? It is only +1 so it should be ezpz for you.

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Blizzard micro-transactions.

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Fear and Scorched Earth, specifically on Dead of Night and I just happened to be playing Zagara.

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You’ll be thrilled to know that we have an upcoming Propagators + Speed Freaks + We Move Unseen weekly mutation! /s (Aggressive Recruitment)

Also it’s on Malwarfare to boot, which means you’ll get props all game because you cannot full clear it at all.

1 Like
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Try the Strettman Infestor spam. I don’t have a duo to run the mutator but that is generally how I deal with it.
If you have two base on DoN because you Solo it, It get even better. If you got an Artanist that left the game, Even even better.

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Photon overload does not activate on mineral shields despite they count as structures.

If you add darkness to propagators you don’t even see where they go on the minimap.

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Omg that’s gotta have sucked

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I’ve never seen a win for leech + diffusion.

Here’s an example with a few other mutators on top, but on DoN it would be a much bigger problem cause a stank would be completely unkillable if it gets close to the base, and hunterlings that manage to get in the base would be unkillable too, the only real chance would be to use terran commanders and float cheese.

2 Likes
Horrible brutal+ How can you even win these?
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I don’t have a ton of experience with mutators, but I have enough to say I hate propagator. Last time I played it I actually got low-key upset. Something about watching my whole army and base turn in to walking boogers triggered something in my lizard brain that like scared me or something? It’s way worse than just getting overrun.

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Yea I’ve only faced against propogators maybe two or three times and it’s been a nightmare each time. It honestly feels worse than Heroes of the Storm depending on what else it’s combined with.