For NA, games are at its peak around 22-23h EST and are 5.5 times more popular than around sunrise.
Same goes for EU at Central European Summer Time, but is 22.5 times more popular.
On the contrary to popular belief, weekend games (Saturday) are only 27% more popular than week games (Wednesday). This means weekend games quality aren’t sufficiently altered by casual weekend players. Only toxicity (alcohol, drug) could alter it sufficiently, but it’s not measurable.