Are you armor and resist capped? Every Torment difficulty you go up, you’ll have a penalty requiring additional armor and resist all to hit your caps again.
The unique chest for Spiritborn QV drains your heath while you have a skill on cooldown.
I didn’t know this at the time and I didn’t have all my uniques for the build, and I was getting one shotted out of nowhere because my health would be draining, then either I end up standing on a poison pool or a corpsebow shoots me from across the room.
Get money and buy a grand one for 20 to 30m. Heck I will give you 3 of lesser versions free if u need. The version before grand. I got tons of skull mats… Urza#1177
Also keep in mind, Temerity barrier is currently bugged…
When you zone through a door, the barrier hp often goes to 1-4 hp, instead of the stat-roll (Which is something like 50-100% of your max hp) However, the visuals for barrier are kind of terrible, so 1hp and 100% hp barrier are pretty hard to tell apart. (you can simply uneqiip and re-equip the item to fix it until you zone and it bugs again)
I died unexpectedly a few times trying to do Torment 2 lair bosses until I realized it was because my Temerity barrier kept getting bugged… so instead of having 3k+3k hp, I had 3k+4 hp.