I cannot speak with Lady Prestor after accepting the 4th part of this quest, after arriving from Lakeshire.
HELP! And it’s not just me, 4 other people were stuck with the same problem in game now…
Is someone doing the Onyxia attunement by any chance?
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Had the same issue when I was trying to finish a DM quest. Had to wait for their quest to finish.
You can’t talk to her if another player already has started the escort phase.
There is no player, i am now alone and she just standing there… I logged off for a few hours and still no love. Left and came back to Stormwind, I dropped and readded the quest, etc.
The escort is a long walk so it’s not always obvious if you’re in the keep. This used to happen a lot in Vanilla.
Not saying it isn’t bugged, but not being able to talk to Lady P. frequently happens because the escort is ongoing 
I hope it works out for you.