I love this affix. It’s basically a “free” week when afflicted is part of the rotation.
Improved dispel + holy word life or serenity on an afflicted. OR, Sanctuary if they are stacked/close enough. Can also flash heal them very quickly if needed. If you have improved holy nova stacks you can pretty much 1 shot heal them with that as well. So many ways to deal with them, although I generally just dispel one and holy word life the other in lower end groups. At higher keys the DPS will dispel them for you so you can use your dispel for dungeon mechanics. 