Let me clarify some things in this thread because there is some bad information for new rogues or rogues who want to get better.
First of all, Envenom does not deal damage over time. It deals a large amount of damage instantly and increases your chance to apply poisons with melee attacks and mutilate for a short period of time.
Second, some have mentioned that having a high envenom uptime is important, and this is true, but there are more important things to consider than uptime, especially in PvP.
To be specific, the most important thing is to pool energy before using envenom, meaning, you must wait until at least 100 energy before using envenom, if not more. You DO NOT want to spam envenom whenever you can, in PvE or PvP.
The reason for pooling energy before Envenom is threefold:
1)Mutilate strikes can apply poisons just like auto attacks. This means that when you use mutilate with the Envenom buff, mutilate will also have a 30% increased chance to apply poisons. If you want to maximize your DPS as a rogue (especially if using double dose traits) mutilate should only be cast during the envenom buff. However, mutilate costs 55 energy and it takes at least 2 to get 4-5 combo points, therefore, if you have at least 100-110 energy before casting Envenom you will be able to cast two mutilates with the extra poison proc chance buff.
- Elaborate Planning is the best talent in the first row. Elaborate Planning increases your damage by 10% for 4 seconds after any finishing move. Therefore, you want to have enough energy to be able to use your 2 mutilates after envenom within the 4 second window of Elaborate Planning. Professional rogues will save up energy until right before capping to full (full is bad, you never want to be completely full), because they will be able to use Envenom -> Mutilate 1-2 times (depending on Crits) until 4-5 cp then Envenom again at the last moment of elaborate planning to get 10% damage on the second Envenom. In fact, with good pooling and crits you can get a chain of Elaborate Planning Envenoms to deal significant burst damage.
3)Need to fit 3 Envenoms within the 9 second Toxic Blade window. The instant damage from Envenom is nature damage, and since toxic blade increases nature damage done by 30%, it increases the damage of envenom by 30%. You DO NOT want to use Toxic Blade on cooldown UNLESS you are able to prepare before hand in such a way as to be ready to burst as soon as it becomes available. You must refresh dots invetween toxic blade casts so that you do not have to spend energy or combo points during toxic blade to refresh bleeds. Likewise, you need to have 4 conbo points and a nearly full energy bar so that you can immediately do: Toxic Blade -> Envenom -> Mutilate 1-2 times depending on crits to 4-5 combo points -> Envenom during Elaborate Planning -> Mutilate 1-2 times depending on crits to 4-5 combo points -> Envenom during Elaborate Planning. If you do it right you should regularly get 3 envenoms during the 9 second toxic blade window with two of them being bugged by elaborate planning.
Now, this is a perfect situation where you are not required to stun the kill target because a team mate is so you may only be able to use two envenoms during toxic blade because you spent 5 cps on Kidney Shot. In most situations, Marked For Death is used as your kill timer for several reasons, and even though toxic blade has a 24 second cooldown it is usually delayed to a 30 second cooldown to line up with marked for death. This also has to do with the diminishing return timer for stuns which is 24 seconds. Basically, only use Kidney Shot and Toxix Blace once per Marked for Death in order to make sure that the diminishing return for stun on the kill target is gone before your big burst combo.
Someone in the thread had mentioned the Azerite trait Twist the Knife, but do not use this for PvP because it has 85% reduced effectiveness in PvP and is too RNG dependent anyways.