The running theory right now is that Azshara is after the Void Lords.
But, as for a bit of background. Take this with a grain of salt as we do not know everything about the Shadowlands yet, but we do know a substantial amount. So, without further ado, let’s start from the basics.
The Pantheon of Death consists of six “Eternal Ones,” this includes:
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The Jailer of the Maw
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The Archon, Kyrestia the Firstborne of Bastion
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The Primus of Maldraxxus
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The Winter Queen of Ardenweald
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The Arbiter of Oribos
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Sire Denathrius, the ruler of Revendreth
Here is a picture of the 6 Eternal ones.
Note that the Maldraxxi-looking guy with the helmet and axe is not the Primus, but his current replacement, as the Primus has gone missing.
These 6 Eternal Ones, again, compose the Pantheon of Death. Each of them created the plane of the Shadowlands they rule over today. Except for the Jailer and the Arbiter. You mentioned how Queen Azshara speaks of the “darkness” Sylvanas seeks to unleash. That is the Jailer. Sylvanas and the Jailer struck a deal back in Edge of Night, a story in which Sylvanas jumped off of Icecrown after Arthas’ death, as her only goal in her undeath had been accomplished.
We don’t know the specifics of the deal, but we know one thing is for certain, and it’s that Sylvanas and the Jailer seek to consume the World Soul of Azeroth by pulling the entire planet into the all-consuming Maw.
But this is where stuff gets really interesting. In the Shadowlands, you will find various “Waystones” which serve as our graveyards in this expansion. But we end up finding a particular one in the Maw that’s slightly different.
During the initial questing in Shadowlands, we discover that this waystone reacts to the Champions of Azeroth. Which is interesting, because, the Titans have absolutely no knowledge of Azeroth. This is when the big bit of speculation comes in, and the potential lore bomb. Ion mentioned in an interview with Bellulargaming that the Titans have creators, and through our questing in the Shadowlands, we also discover that the Shadowlands has creators as well.
They are called the First Ones. They are the creators of Oribos, the Arbiter, and supposedly the Shadowlands as well.
So, potentially, this could mean that yes. We have a new seat of power in the Shadowlands. These First Ones, could potentially be the creators of not only the Shadowlands, but the Titans and all of the current cosmology of WoW. We still have an entire expansion’s worth of story to get to, and this is obviously going to be a developing plotline, so all we can do is wait and see what happens.