After the patch on Tuesday October 17, my game would crash with an error 132 on initial load of the game after the character screen or on a reload like after getting into a dungeon. I worked with Blizz tech support for a week and unfortunately none of the troubleshooting I attempted (using the scan/repair tool, reinstalling the game, loading w/o addons, etc) worked to fix the issue.
I then stumbled upon the answer. It was the Xbox Game Bar. Apparently, game DVR programs like it can cause error 132. Search “Capture settings” in Windows, click Xbox Game Bar in the menu on the left of the window and then toggle off the game bar. Try turning off NVIDIA’s DVR as well if that didn’t clear the error.
Hope that works for you! It cleared up my issue after a week of being unable to play the game.