Pick a character, choose how they die, and they cannot be resurrected or brought back in any way.
Character: Malfurion Stormrage
Cause of death: Tyrande divorces him causes him to become depressed and succumb to the whispers of the void who promise they can win his beloved back turning him into a void druid that we have to put him out of his (and our) misery once and for all.
Cause of death: We find out even death cannot stop Garrosh, his rage transforms him into an avatar of the old gods. He wipes the floor with thrall who dies sniveling for help.
Chromie, forever stuck in a timeloop devoid of time and space rewatching her cringe cinematic with iridikron, she eventually dies from her own cringe self and the world is better off.
Jaina- Due to all her tears and whining during WotLK, her eyes and vital organs have dried up completely. Frost magic has frozen her blood and she dies of raging diarrhea.
Baine Bloodhoof was rescued from Torghast early in Shadowlands and he sat down in Oribos to rest. And he sat… and sat… and sat… Until one day he died.
But, upon his death he was sent back to Shadowlands into the exact same spot where he continues to sit till this very day.