Sanguine depths is one of the tougher dungeons in pugs especially. Coordinated groups go smoother but still hit rough patches.
For first boss, make sure you are staggering orb soaks. Also immunities are super super useful here if you have any as they can solo the charge, reducing the healing your healer needs to output.
Invis skips are also king here. Depending on where you want prides I usually invis skip just before the bridge (this includes the pack before AND including the mini boss). Those overseers are rough though and if you lack kicks you can opt to skip the second and third overseer pack and just pull the mini boss instead (this will give pride, otherwise you have to pull the room to the left before the bridge to line with second boss still)
Second boss is rough. If it’s tyrannical you will want to stagger cooldowns for add spawns. If you have any classes with aggro drop (rogue hunter and I think mage can do it or night elves for ally) and they can stop the castigate immediately after it starts.
Third boss is another immunity cycling game. This fight is a lot lighter on your healer if you have enough immunities to cycle on the burst she does. This leaves more orbs for the group and very minimal outgoing damage after.
Gauntlet sucks pretty bad but make sure dps are using personals and health pots when available to save your healers mana. There are points they can spam drink if dps burst the dogs.
That awful trash pack before the gauntlet can be invis’d but in a pug this can be quite risky and a wipe means gg. You can instead choose to skip the very last pack of the gauntlet which a roughly the same mob makeup.
Last boss bleed can be dodged if you are the second person and are moving. This will also save a lot of mana for your healer in case someone gets a double stack. Basically always be moving and pray you get lucky.
A lot of pugs don’t know the tricks in there and that’s what really breaks the keys. I see a lot of people in 15’s/16’s not line prides with every boss. I also on my druid tank notice people complain when I do invis skips and respond with “nobody ever does it like this” which simply is not true and I alert them prior to dungeon start and nobody says a word until it gets messed up .-. Pugs will be pugs I guess
Side note though, I’m not arguing against the fact this dungeon is overtuned by any means. I’m just saying if people change the standard way they run it with pugs it becomes more manageable.
You should have pride for each and every boss. After second this means pulling more until you have 74-75% before dropping into third boss room.