Interface glitch - mouse randomly selects action on right toolbar

My husband and I have been have a strange problem. It seems to only occur with characters that have been to Zereth Mortis (ZM), and it happens more frequently in ZM than other zones. Our interface glitches and we will try to click on an item or an action on our tool bar and another action on our toolbar activates, which we have narrowed down to actions on our right-most vertical toolbar. He has went through stacks of food wondering why nothing appears to be happening. This has been happening for a few weeks now and we did not know how to describe it at first. Sometimes /reload ui works, sometimes we need to log out and back in, a couple of times we had to hard close(“x out”) because trying to hit the logout key was not working. In addition, we occasionally lose our nameplate and the associated health/info bars. When this happens we luckily have each other to keep an eye on our health. Please look into this. It happens at least once a night to each of us and we have not idea what precipitates an occurrence. Our guild mates have had similar happen to them, too.

UPDATE (4/11):
This is still happening and now we have noticed it happening on lower level characters that have not been to ZM. Occasionally the right or left mouse button randomly selects an action on the right most vertical toolbar. Most of the time when this happens, none of the other hot-keys (i.e. 1,2,3,w, etc.) will work and they also activate a right most tool-bar action. Sometimes I can hit enter and I am able to do a /reload ui, sometimes not. Please someone help!