First time I can recall seeing this.
At roughly 7pm EST today, I zoned into the arrival room for people porting in to Northrend Dalaran. I went afk for a few minutes, but when I came back, my camera had shifted dramatically. My character was off to the left side of the screen, and the camera did not rotate back into place when my character started moving. I solved it by targeting myself. But then when I went into the room with the gear vendors and targeted a vendor, it shifted everything to the left again.
I noticed four separate shifts in camera alignment. The smallest shift to the left was when clicking on one of the non-interactable NPC guards near the Violet Hold and the flight master. The next-largest shift was when clicking on the middle banker of both banks. The third-largest shift (shown in a screen shot) was when interacting with a vendor where you can get a few tier pieces. The largest shift was when interacting with the human repair vendor in the back left corner of the engineering shop.
I’m going to restart the game after posting this thread and see if I need to report it again.
Edit: I don’t know my monitor’s dimensions, but the native resolution is 1920 x 1080.
Update: Restarting seems to have solved the issue for now, but I’m leaving this post up in case anyone else has been, is, or will be experiencing this same issue.