Something I thought would be fun.
Do you have unique actions binded to different keys?
I have a few below and would be interested to hear others people may have.
Baptiste
Lucio
Winston
I’m QWES for movement, and 1,2,3 for my abilities. I couldn’t get past the muscle memory from my MMO days haha. I think I’ve only met 1 other person that does this.
Roadhog
Left Click = hook
Thumb key = shotgun
Right click = Ranged shotgun
C = melee
E = heal
Shift = Heal
Zarya
Scroll up = projected barrier
Scroll down = personal barrier
I only rebound crouch to alt because I can’t reach ctrl/my hand would be super uncomfortable and in a weird position.
I think I’ve seen maybe 3 people who have that setup.
2 of them were Rein players 
Hold onto your socks…
I use home, end, insert and page down for movement. \ for crouch.
Both insert and page up for jump depending on what feels right at any given moment (not thrilled with this last part but I’ve become too adapted to it after years of using it).
This config allows my left thumb access to the number pad for quick weapon swaps and other tools in games like Unreal Tournament, Doom, etc.
Num 7 is my reload in every shooter. Ult is a mouse button.
I’ve decided that the default bindings suck and make the keyboard feel clunky to use, so I’ve made some great changes in my opinion. Also I use a left and right foot buttons so my feet can interact as well.
Default:
Quick Melee is mouse thumb button
Sigma:
Barrier: left foot pedal (or E if not pedal)
Rock: right click
Quick Melee: right foot pedal
Zarya:
Projected Barrier: left foot pedal
Reload: right foot pedal
Hammond:
Transition between Mode: left foot pedal
Quick Melee: right foot pedal
Shields: shift
Grappling hook: left click
Primary fire: right click
Toggle grapple: On
Reinhardt:
Barrier: left click
Primary fire: right click
Fire strike: mouse thumb button
Orisa:
Barrier: left foot pedal
Reload: right foot pedal
I don’t really play any other heros, so that’s about it. I highly recommend foot switches because I find the game much more interactive when you use more parts of your body to engage with the game. Especially with sigma where multitasking shield usage and using Melee in-between attacks. Using your feet helps multitasking capibility in my experience.
Everything is pretty customized for me. I use EDSF for movement, Shift and Tab for abilities, A for ult and V for jump (I use my index finger for it). Everything else is built around that. Reload is middle mouse click.
A few exceptions: Scoped weapons (Ashe, Widow and Ana) I use shift to zoom in, and I put Pharah’s concussive blast onto RMB.
Haha! I’m a zen main at heart. McCree and Ashe would be my secondaries. I do love me some rein when I play tank though.
Esdf for movement, W and R for abilities, c for crouch, mouse 4 for reload and mouse5 for melee.
Reinhardt
Fire strike bound to M4 which I use for quickmelee on everyone else(page back button on most mice)
Zenyatta
Discord is additionally bound to scroll down and Harmony is bound to scroll up for more reactability
And on a number of heroes, I have reload bound to scroll down because it’s just easier
I have all E abilities on M3. And my ult on E and voice on left-alt.
the only one i have special bindings for is for lucio and i don’t play him that much.
Right Mouse Button - Jump
Mouse button 5 - Boop
Mousebutton 4- Melée
SpaceBar - Crossfade
Shift - Amp it up.
saw a high ranking lucio have it that way and i tried it and it actually increased my ability and my enjoyment with the character a lot personally.
I’ve changed Moira’s primaries, because it matches up better. Because why click right when you’re firing from your left, and vice versa?
Nothing character-specific on PC, but I use a few rebound buttons in general:
On console, I remap the jump buttons for Lucio, Mercy, and Pharah to left trigger, so I can aim freely while flying/gliding/wall riding.
zen - sw^ harmony, swdown discord
melee - F, for “fighting”
The only default bindings I change are moving melee to the side mouse button and push to talk gets put on the mousewheel button
Lucio – off/on main for a while. Absolutely had to change his jump/ride to right click. Mashing space bar on him is just cumbersome.
I tried something similar, couldn’t get used to it. Even though I think Hook on Left Click is a really smart setup. 
Widow:
I really don’t understand why so many people don’t do this. It puts much less stress on your index finger and you have less force holding back your flick accuracy.