Overwatch makes mouse buttons not work outside of game

At some point while playing the game, mouse buttons become unusable outside of the game even after the game has closed. This happens exclusively on overwatch, keyboard can still be used to navigate and interact with other applications and the cursor can still be moved. Just the mouse buttons become unusable.

Anyone know what the problem is / how to fix it?

changing display modes, tabbing in and out and disabling/re-enabling overlays has not yet fixed the issue.

Its like sombras hacked my mouse! >:(

This is not the Tech Support forum. You should delete this and repost over there or open a support ticket so they can help you troubleshoot individual issues like this.

My guess is it might be caused by a software mapping mouse controls that’s not setup correctly.