Ensure that you are not affected by the need to update your BIOS drivers, since you’re using a Ryzen CPU.
Overwatch and drawing tablets don’t seem to be friends, try unplugging it while playing.
Are you affected by the Chroma issue with Overwatch?
When gaming, your power settings should be on High Performance if you want to get the most out of your hardware.
The MSI tool controlling lighting effects seems to be crashing.
I’m going to guess your home equipment is designed to not respond to most pings, because you wouldn’t be able to reach most of the internet with a 95% loss. However, the hops directly after your equipment are showing some very concerning numbers for their packet loss, and I definitely recommend calling your ISP and having them check your lines.