Mouse stuck on screen and all input gone

Recently in a comp game (51X6B7) near the end, my in game mouse appeared on screen and all of my inputs were disabled ingame. i tried alt tabbing. alt+enter, f11, esc, windows key+enter you name it. nothing worked and i ended up getting kicked from the game. all i did when it happened was turn up my audio on my hardware audio switch. I really doubt that was the cause tho since nothing similar has ever happened before.