just curious what unique setups you guys use (if any)
like i for one have always switched dooms default slam (shift) and uppercut (E)…same for OW2 (powerblock on E)
for sojourn i liked the feel better of flipping her primary and secondary (charge shot on left click)…i experimented with the same before on soldier…might do again once OW2 hits to not get confused between the 2
what about you guys?
On console, it’s absolutely necessary that you swap the triggers for Moira so that her hands match the triggers (left trigger = healing/left hand; right trigger = damage/right hand).
I swapped Interact (L3, Playstation Player) for Right D-Pad on Sombra cause I kept accidentally destroying my Translocator.
I have one button specific to Dva’s voiceline spam tech. Pointer finger button to the right of movement keys. “LOL LOL LOL HUEHUE”
Very important to have.
I have micro missiles on my mouse on a side button. I never use E for her abilities. Too much need to keep your fingers on the movement keys.
I have more than half the roster re-binded.
I find it annoying that you can’t unbind reload for the characters that don’t need it, because if you do you can’t swap characters in spawn once the match starts.
I swapped Ana’s grenade and sleep dart.
It makes the most logical sense to me and feels better overall.
I usually bind left bumper to be healing/get out of jail (e.g., Ashe’s coach gun, Bap healing burst, Ana nade, etc.). I have strong muscle memory to hit LB when in danger due to playing a ton of Moira (LB is her fade).
Tracer (for as infrequently as I play the character) I always rebind blink to MB2.
Zenyatta: I also have Discord bound to Mouse Wheel Down and Harmony to Mouse Wheel Up.
Then there are a ton I also bind to Mouse Wheel Down more as reactions.
I play half controller half mouse, so many of my keybinds are non-standard. Q for ult? Lol no, M4 is ult. M2 for alt fire? Nah, M2 is jump. 
Some heros have different keybinds for the same ability. ie melee is left stick down for most heroes unless I’m Ana in which case it’s LB on my controller. And for Mercy? Melee is mouse wheel.
Roadhog,
Hook, Left click
Ranged shotgun , Right click
Shotgun, Thumbkey
Heal, Shift and E
Melee, C
Duck/Crouch on mouse5 for Mercy’s loadjumps. That’s it.
Some characters I have weapon swap on scroll up. Mei’s ice wall on mouse 4/pageback. Quick melee on scroll wheel down.
Since release, I have yet to play her that way.
this is a great idea…same with roaghog’s hook and heal