Today I had an issue where mouse1 and mouse2 were suddenly not working anymore while playing Zenyatta. The mousewheel and aiming was still working though. I turned my mouse (GPW) off and on, didn’t help. Removed the USB receiver from the PC and put it back in, didn’t help. On the desktop the buttons were working normally.
What helped: Running back to spawn, swap to another character and back to Zenyatta. After that mouse1 and mouse2 were working again.
Is this a new bug or did someone have this issue already in the past? I have ~2000 hours of playtime and never had any issues like that before. The only thing I remember was a similar bug with Moira when she was new.