Played with 100’s of female gamers over the years of gaming on multiple games/platforms etc… Most of which have been better than me at gaming.
Treat them as any gamer, they give as good as they get. I wouldn’t let some little spotty pre teen male worry you to be honest.
A real gamer doesnt see gender and just wants to play the game, as long as you do your role to the best of your ability who cares if you win/lose/draw.
I would play with a space chimp if it increased my chances…
But don’t feel like you have to change who you are, embrace the nice gamers and block the idiots 
Happy Gaming all
Cruel