Geoff Goodman was once asked what was the most overpowered balance change they made.
His answer:
I’d say at this point its pretty clear Brigitte’s initial balance was pretty far off the mark. She has been nerfed multiple times since then and she is still very strong.
Source: Geoff appreciation thread - #48 by GeoffGoodman
Brig was still pretty OP when people ran a 2/2/2 comp. So I do not see how she can not be OP in 222.