Leaving loot on the ground can be detrimental if you’re trying to loot and your bags are full, Returning to Town is a huge No! Doing so, will not only cause you to lose the loot on the ground, but also reset the Dungeon progress along the way.
I’ve tried this many times, but only as a solo person. Mid-Dungeon and at the end of a Run of a Dungeon Boss Kill. Once you leave via Town Portal, Not the Emote Leave Dungeon button, The actual Town Portal with T as the assigned button.
I was doing it okay yesterday, and it seemed to have worked, but today not so much. I wanted to bring this forward as I haven’t encountered this before. Perhaps, it was a Memory Leak?
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+1
Dungeon reset on town portal loot dump; This behaviour is entirely unexpected and undesirable.
Desired behaviour - allow loot dump runs! TP already warns that portal will be lost if leaving town.
Potentially add dungeon reset counter while in town?
Has been happening to me and my wife as well - the game starts you at the beginning of the dungeon. However, quest items like the journals that you pick up still saves. Never happened in the previous betas.
In multiplayer, if one person stays in the dungeon and waits for the rest of the party to go to town, then you won’t lose progress. That’s what we’ve been doing for now.
I usually run solo since I don’t have any friends to play with. 
But this is new for me, since It wasn’t like this last night. So somewhere between logging off last night (early this morning around 5:30am est) and the time I logged back in around 9am est.
Blizzard has confirmed this bug.
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Agree - TP from a Dungeon to Town, and back to Dungeon, should not reset your dungeon, Unless you go from Dungeon to town and then run out of town or start participating in another event (Outside of Town).
Returning to Town to complete a loot dump, or to complete a Quest inside of town should not reset your dungeon. So a Timer would be warranted. 3-5 mins should be enough to do what you need to do. Even if it’s to run to the bathroom and come back real quick.
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Can confirm, experiencing this as well and it’s not even a checkpoint reset, you start over fully at the beginning. I just did this in Dead Man’s Dredge after I’d made it through the barrier, did a loot dump, and now I’m back to collecting Animus. This kind of ruins the functionality of the portals.
I feel like I should add that it not only resets progress, it generates a whole new version of the dungeon, as well. May be unloading the dungeon when you portal out.