I have been seeing (rare?) inconsistencies of objects/enemies/(more?) not spawning, but having the work-around of going to another region with monsters (not going back just to town) then coming back to get the region to reload to fix anything missing.
One specific example I recorded:
Quest: Perceived Threat
Objective was to investigate corpses and bring back a sample from the best one.
There should have been 3 or more corpses spawned.
Only one corpse triggered/spawned.
Tried abandoning the quest, reclaimed it, but then none triggered/spawned.
I left region and came back as explained above, then they triggered/spawned and I was able to complete the quest.
In the beta I reported this exact issue with Lilith statues, and I fear it is a common occurence for them still for everybody, just few actually notice it until they bring up a guide to assist with any they could not find themselves, and end up being at places they know they already checked, or worse be at a location for a known spawn and for it to still not be there.
Quests, this has been rarely an issue from there being extra spawns as back-ups or conveniences to make the quest easier to not need to find the “exact spawns” in a large area.
Some regions have been completely empty of enemies and players, but then come back a few minutes later and it is packed to the brim.