Quest checkpoints disappearing

Don’t know if anyone else is experiencing this but I’m finding that anytime I’m trying to either approach one of the blue exclamation marks or the blue diamond marking a quest’s end point that the moment I cross over into the region containing said marker then just disappears. I’ve even gone to the end-point location and tried to teleport to a city then come back and it’s strange - every NPC that would normally be in that area is just gone.

I have also had that occur when, for example, just today I teleported to the city Jirandai (I think that’s how it is spelled…) to drop off gear during a helltide and when I arrived in the city every NPC normally there was just gone. I could use the stash and then just ran out of the city and enemies started to appear but it seems like a strange occurrence.

Thanks!