Good morning Sebix. Blizzard does not allow any third party software use that touches their games, in any way. Esp if it gives information or advantage beyond what the base game provides. WoW addons are made within a Blizzard provided LUA sandbox and only modify the display in ways Blizzard allows.
D4 does not have that. If Overwolf touches or pulls any real time game info or game files then you don’t want to use it. Blizzard put out a statement on it not so long ago and it is pinned at the top of this forum.