I have only noticed this issue with season 15. Chests, Pylons, Objective Corpses. Basically, all interactables that aren’t items I have been having trouble interacting with. I have to move my mouse around the object much more than normal before the label appears / I can click on it. Its almost like the hitbox got smaller on these interactables.
This is especially annoying in Undercity because it takes an extra couple of seconds to interact with beacons.
I created a video example, I dont have permission for links so this will have to do:
https://streamable.com/r6rj50