I am experiencing hard crash/reboot when talking to NPCs in towns, or sometimes when using NPC items, like an anvil.
This happens only the first time I speak to an NPC or interact with an anvil. Subsequent conversations or uses are fine.
My PC will hang, and then reboot.
Older machine, but has no issues in-game outside of this.
Windows 10, 16GB RAM, running on an SSD, and a GTX1660 Super.