With bosses, dungeons, helltides etc, I’m only able to pick up a fraction of the things that drop the rest are just pictures I can’t interact with on the floor. I’ve tried restarting, going to different areas, same issue everywhere.
Sounds like you have a loot filter turned on.
Human error confirmed - It was me messing up my loot filter setup. I shall go hang my head in shame, thank you!
All good!