Level matters yes.
At level 100 with the right paragon and gear you can have quite a lot of life and dr.
I have 50k life at level 100.
30.8% All Damage Reduction
36.1% vs Close
A little Distant and Bleeding.
Build is focused on reaching max Fortify as quickly as possible (pretty much instantly) and staying at max. Also Chance To Heal is surprisingly beneficial.
All res maxed. However, I have overmaxed res at 76.7% all. But even at just standard max res they couldn’t touch me.
10k Armor which is more than you need. I think you need 9200 something for max armor cap.
The big boosts to life make a HUGE difference. Trust me.