Game Flickers or Crashes When Left-Clicking – Only in Diablo 4

PC General Discussion
1

I’m experiencing a persistent issue in Diablo 4 where the screen flickers or the game crashes whenever I repeatedly left-click. This problem only occurs in Diablo 4 — other games work normally.

Here’s what I’ve already tried:

  • Updated and reinstalled NVIDIA drivers (GPU: RTX 3060 Ti);
  • Tested a different mouse and changed polling rate (from 4000Hz to 1000Hz);
  • Adjusted resolution and display mode (monitor is 1080p 144Hz);
  • Disabled all overlays and background applications;
  • Verified game files and reinstalled the game;
  • Ran sfc /scannow and DISM to fix any Windows file issues (Windows 10 Pro, version 10.0.26100.4484).

The issue persists after all these steps. I suspect it might be related to the high polling rate of my mouse (Redragon M916).

Please investigate this issue. I’m happy to provide logs or screen recordings if needed.

2

AI’s fix:

Lower your polling rate to 500Hz or 250Hz

    1000Hz wasn't enough for me — only 500Hz fixed the crashes/flickering.

Add launch options in Battle.net:
Go to Game Settings → Additional command line arguments, and add:

-force-d3d11

(Optional: try -force-enable-vulkan instead)

Disable NVIDIA Reflex in the in-game settings

Use Windows default mouse driver:

Go to Device Manager → Mice

Uninstall any Redragon-specific driver (if installed)

Let Windows use the generic HID-compliant driver

Disable Fullscreen Optimizations:

Right-click Diablo IV.exe → Properties → Compatibility tab

Check: “Disable fullscreen optimizations”

Check: “Run this program as administrator”

Try with a basic wired office mouse at 125Hz — useful for isolating the cause