Well.
To be honest, more people with higher end cards were having problems than those with lower end hardware during the first month after launch, funny enough.
Especially those on 3080 and 3090 cards. And a lot of Gigabyte cards had failures playing the game. But that’s due to a problem with the card quality and build than the game. It just stressed them hard enough that they failed prematurely.
I run an MSI card here, but I bought it used, blind off of eBay for a really good price. Got lucky I guess, installed it the same day the game launched (early launch date, not official launch date)
But honestly, mine has been near flawless. I had some adjustments that I cycled through, but my current list of settings for my desktop can be found here:
-Full breakdown of a system that plays Diablo IV without problems:
This is still the current setup for that tower. My laptop has more recently been changed, and at some point I should go over that in a similar fashion.
But I maintain 3 systems that play the game, 1 is my father’s OMEN laptop. His has been operating fine as well, but he is still running the older driver 535.98 that my desktop is.