Have you tried using DDU and going back to an older driver?
Not sure if it will help or not, but I know some have had good luck with the drivers from August. I’m running on the driver that was out for the game’s launch. It was the May 30th version. Still using that driver, been working fine so far.
Make sure your swap file is set to the same drive as the OS, (or on the default settings). Some people have tweaked with this, and caused issues. I personally have mine completely disabled, as I didn’t need to be using it.
Here, you can review my desktop settings to compare with your own:
-Full breakdown of a system that plays Diablo IV without problems:
Changing to an older driver:
-For those of you that have an Nvidia graphics card and have the following issues:
Good luck.