Elgato Wave Link - Windows Defender - And Diablo Crashing

General Setup (Running Software)

WaveLink - (For a Wave XLR device)
Stream Deck
Razer Synapse
Voicemeeter

(I only mention Razer because lots of folks mention shutting it down, but I see/saw no reason to)

So, this has NEVER happened to this PC prior to running Diablo4, which is why I’m bringing it up here.

When I am running D4, after some period of time, my Wave Link audio devices completely die. Wave Link crashes, and restarts, but at a CRAWL. Voicemeeter hangs. All my USB peripherals seem to crap out, and anything related to audio is kaput. D4 then hangs, and becomes unrecoverable. I have to kill it, and reboot to continue to use my PC.

Now again, this has NEVER happened prior to running Diablo 4, and I use the PC a LOT. I capture/stream games quite often, and never have I had this occur.

What I found, what EXACTLY at the time of the crash, WINDOWS DEFENDER has updated, and has started a new Definition Service:

A service was installed in the system.

Service Name:  MpKslffdd25fa
Service File Name:  C:\ProgramData\Microsoft\Windows Defender\Definition Updates\{476948AD-C6A3-4A09-BC08-59719E59F840}\MpKslDrv.sys
Service Type:  kernel mode driver
Service Start Type:  demand start
Service Account:  

This happens EVERY TIME this crash occurs. At the exact same time, there is a service that gets installed along with the Definition updates.

I shut down Defender, and played the game all night with zero issue. While I understand this seems like its related to my system, I assure you that this has never happened prior to running D4. Any thoughts on this?