Diablo 4 Crashes or Flickers When Clicking Left Mouse Button

Hello,

I’m experiencing a very specific issue in Diablo 4. The game flashes or sometimes even crashes when I click the left mouse button. This issue only happens in Diablo 4 — I’ve tested multiple other games (like PUBG) and they work perfectly.

Here are my system specs:

  • GPU: RTX 3060 Ti
  • Monitor: Full HD 144Hz (single display)
  • Mouse: Redragon M916 (originally set to 4000 Hz polling rate, now lowered to 1000 Hz and 500 Hz for testing)
  • Windows Version: 10.0.26100.4484 (fully updated)
  • Game installed via Battle.net, all files verified

Things I’ve already tried:

  • Lowered mouse polling rate to 1000 Hz and 500 Hz — issue persists.
  • Tested different DPI settings.
  • Ran Diablo 4 with administrator privileges.
  • Disabled all overlays (Battle.net, Discord, NVIDIA).
  • Switched between DirectX 11 and DirectX 12 using launch arguments (-dx11 and -dx12).
  • Changed display mode between fullscreen, windowed, and borderless.
  • Reinstalled GPU drivers using DDU (clean install).
  • Created a new Windows user profile — problem still occurs.
  • Tested a second mouse — same problem only in Diablo 4.

Important: the issue only occurs when I click the left mouse button in Diablo 4. Right click and other buttons work normally. There are no input issues outside the game or in other titles.

This seems like a compatibility bug between the game and specific mouse input behavior. I’d appreciate if this could be escalated to the development team, as it makes the game nearly unplayable.

Thanks in advance.