I have logged in about 30 minutes ago into Battle net and then the Diablo 4 client started an update. After the update I tried to start the game but I keep getting the same error “Game initialization Failed: U” and the game is not starting. I must mention that previous to the update the game was working fine.
Same problem but it happened after installing Kaspersky Antivirus, so I believe that’s the cause. The problem is I am WFH and have Diablo installed on my work PC, with no control over the AV software.