Toxic D2 Purists

You get the same numbers with hypergeometric assuming a reasonable population size. Both calculations were shown in another thread.

A hypergeometric does exactly what you say. The percentage is the same to the first decimal place.

You will notice I did not say binomial distribution and left it vague. Of note, 52.7% of never meeting a cheater among 21 ditinct players is the same mathematically as saying that 47.3% of the time that you will encounter at least one cheater (100%-52.7%=47.3%)

You do still pick up items from monster drops.

It is a cat and mouse game. In FFA multiplayer loot, cheats are a problem because they can get a disproportionate amount of good drops. In personal loot, they can not. It is not about detection per se but the direct effect on legitimate players. The precise way Blizzard detects bots is obscure for obvious reasons. It is not simply clicking speed (I assume).