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Widow’s Pauldrons
The damage over time dealt by Gem of Efficacious Toxin stacks up to 500 times when applied by your permanent minions. Secondary skills deal 50% reduced damage.
(Necromancer Only)
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Explainer
When Mirinae, Gem of Efficacious Toxin is equipped, Permanent minions now apply several stacks of Damage Over Time from Gem of Efficacious Toxin, dealing up to 500 instances of Damage Over Time in parallel, leading to great damage.
Gem of Efficacious Toxin + Damage over Time
https://diablo.fandom.com/wiki/Gem_of_Efficacious_Toxin
https://diablo.fandom.com/wiki/Damage_Over_Time