Actually am curious regarding Blighted Marrow rune.
Since when you fire the spear it will get all the buffs / modifiers etc, when it hits a mob and gets the 15% is that added to base weapon dmg or to TOTAL dmg when fired?
Cause if it’s 2nd case, then a high crit on 1st mob would greatly increase the dmg for 2nd mob (since it would be let’s say 50T and you increase that by 15%).
Otherwise, in current season am opting for Blood Spear rune for GR100-120 runs / speeds. It’s more consistent dmg and can adapt and do well for various PuG 4m GR you are in, be it elite hunting, or see 10 mobs kill 10 mobs and move on, or making big pulls then activating pylons etc.
With Blight you have to get good density to get most out of it, and also prefer to position the elite / champs on the other side of the bunch - works much better in fixed groups of course, but for quick GR / gems levelups / XP Blood will do better in most scenarios - IMHO.