Running rifts about every other rift if get a killed monster that continues to inflict damage. It looks like a shadow as I can run thought it but cannot attach it. Most of the time it occurs at the end of the run. It kills me while picking up loot or upgrading my gems after the boss is killed. Happens on multiple character classes on both rifts. Have not seen in running bounties or normal game play.
Yes – known issue… see #7 of Player List of Known Issues - Bug Report - Diablo 3 Forums .
You can try to drag it away… and then run back leaving it behind… depending on your build. You can try dragging it to the portal for the next floor, go through it, TP to town and run through the entire dungeon to the loot. Essentially, you need to drag it away from where the loot is so you can come back to it and pick it up… without getting attacked.
Good luck !
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