Globally agree, all changes have an impact and The Devil wants sacrifices, not QoL!
Btw, I’m currently playing the game in SP mode without any 3rd party program: the biggest challenge is to handle the stash room ! You almost can’t do several things in parallel (i.e store items + runes for RW + gems for craft).
However, this constraint is maybe a bit excessive since you can’t even keep some stuff for another character (making low-level set items totally useless, for example), or for MF, or for a major respec of your character (that you may want to do only when you have several pieces of stuff).
I’m happy with the QoL improvements of the Alpha. More isn’t really needed according to me, but I’ll play D2R whatever changes it will contain.