All,
After reloging into the game for a mind-blank of a holiday, i have noted that the audio has had issues on my computer.
Notable fixes were to changte the Nvidia HD audio to off, and to change any windows HD audio off as well.
However, this did not fix the issue with Diablo 3.
To solve the issue, I had to upgrade the audio channels to 128 under the sound options within Diablo 3. I have no idea why the updates to D3 caused this issue as it wasnt an issue for 10+ years previously… but I just wanted to explain a solution
/cheers