as troubleshooting:
A) I have moved D2:R to nvme disk
B) re-installed from the installer
C) checked the file consistency
I have hecked the Task Manager. The game is alive (CPU and RAM values are changing) but it lags. I have seen similar behaviour by some other (non-related apps) and it was due to connection (rather the response) from the server while the client waits for the response.
Mac Pro, 3.1, 32GB RAM, 1060, Windows 10 - current. nVidia drivers updated today. (Actually re-installed Windows today so this is a clean installation.)