Mouse Issue That Just Started

I have been using a Razer Death Adder for years and yesterday when panning with the left click mouse button all the sudden I cannot get the left mouse button to do anything. I have to use the middle wheel or alt-tab to reset it. Then I used a Viper Pro V3 and the same thing. I have no overlays on my GEForce, no addons running, and fresh interface, cache and wtf and even redownloaded the game and still I can use the left button to look left or right and then the left does nothing. Can click on anything to interact or even target anything.

Anyone else having this issue?

Thanks