Two quests:
World Quest: Keys of Loyalty: When I made the key, I died and came back to turn in the key I had just made. The key was gone so I was unable to complete the world quest. I farmed the reagents to make a new key, and it made the repeatable key ([Restored Obsidian Key]) so now I cannot complete the world quest. I farmed up additional mats and now it says “Missing Reagent key fragments” instead of creating a new key. I have 8 [Key Framing] and 94 [Key Fragments] in my inventory.
Duck, duck, Trap: I had 11 meat in my inventory and I could not set the traps. It said, “Missing reagent: Bluebill Meat”.
The above issues are in order of occurence, so I think somehow the issue with the key is bricked all quests for me that require a reagent, though that is purely speculation.