Talent wise the icyviens guide is a whole mess, there a few builds for SV and honestly you have much more room to play around with talents than other hunter specs.
For example, Hydra’s bite is actually really strong in Mythic + unless everything is dying in seconds, so the talent only gets stronger the higher the keys you push as it makes spreading serpent very easy.
TBH every SV hunter talent row has at least 2 viable options so there is a lot of room to play around with it.
With that being said, people who recommend stuff like:
They need to be stopped and cancelled.
This is not a dps fix and yes i will fight you on that. Even if you were running a Mongoose heavy build you would still want to apply serpent sting outside of your mongoose bite windows, Serpent sting benefits from our mastery just as much as mongoose bite, the only time you can StOp UsInG SeRpEnT sTiNg is maybe in open world questing, this recommendation will ruin someones dps in a mythic plus setting or a raid environment.
If you are running the BOP build with vipers venom then yes you can forget about serpent sting until the free procs happen, but you are still using serpent sting.